Alport Syndrome Pathophysiology

Alport Syndrome Pathophysiology

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Hypertension is usually detectable by the second decade of life. Edema and nephrotic syndrome are present in 30-40% of young adults with Alport syndrome; they are not common in early childhood, but their incidence progressively increases with age. With onset of renal insufficiency, symptoms of chronic anemia and osteodystrophy may become evident.

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