Alport Syndrome Pathophysiology

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Alport syndrome is a genetic disorder [1] affecting around 1 in 50,000 children, characterized by glomerulonephritis , end-stage kidney disease, and hearing loss. [2] Alport syndrome can also affect the eyes, though the changes do not usually affect sight, except when changes to the lens occur in later life. Blood in urine is universal. Proteinuria is a feature as kidney disease progresses.

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